Health-related quality of life after myocardial infarction is associated with level of left ventricular ejection fraction.

2.50
Hdl Handle:
http://hdl.handle.net/10143/52973
Title:
Health-related quality of life after myocardial infarction is associated with level of left ventricular ejection fraction.
Authors:
Pettersen, Kjell I; Kvan, Elena; Rollag, Arnfinn; Stavem, Knut; Reikvam, Aasmund
Citation:
BMC cardiovascular disorders 2008, 8:28
Additional Links:
http://www.biomedcentral.com/1471-2261/8/28

Full metadata record

DC FieldValue Language
dc.contributor.authorPettersen, Kjell I-
dc.contributor.authorKvan, Elena-
dc.contributor.authorRollag, Arnfinn-
dc.contributor.authorStavem, Knut-
dc.contributor.authorReikvam, Aasmund-
dc.date.accessioned2009-03-09T11:17:52Z-
dc.date.available2009-03-09T11:17:52Z-
dc.date.issued2008-10-12-
dc.identifier.citationBMC cardiovascular disorders 2008, 8:28en
dc.identifier.issn1471-2261-
dc.identifier.pmid18847506-
dc.identifier.doi10.1186/1471-2261-8-28-
dc.identifier.urihttp://hdl.handle.net/10143/52973-
dc.description.abstractBACKGROUND: The objective was to explore the relationship between left ventricular ejection fraction (LVEF) assessed during hospitalization for acute myocardial infarction (MI) and later health-related quality of life (HRQoL). METHODS: We used multivariable linear regression to assess the relationship between LVEF and HRQoL in 256 MI patients who responded to the Kansas City Cardiomyopathy Questionnaire (KCCQ), the EQ-5D Index, and the EuroQol Visual Analogue Scale (EQ-VAS) 2.5 years after the index MI. RESULTS: 167 patients had normal LVEF (>50%), 56 intermediate (40%-50%), and 33 reduced (<40%). The mean (SD) KCCQ clinical summary scores were 85 (18), 75 (22), and 68 (21) (p <0.001) in the three groups, respectively. The corresponding EQ-5D Index scores were 0.83 (0.18), 0.72 (0.27), and 0.76 (0.14) (p = 0.005) and EQ-VAS scores were 72 (18), 65 (21), and 57 (20) (p = 0.001). In multivariable linear regression analysis age > or = 70 years, known chronic obstructive pulmonary disease (COPD), subsequent MI, intermediate LVEF, and reduced LVEF were independent determinants for reduced KCCQ clinical summary score. Female sex, medication for angina pectoris at discharge, and intermediate LVEF were independent determinants for reduced EQ-5D Index score. Age > or = 70 years, COPD, and reduced LVEF were associated with reduced EQ-VAS score. CONCLUSION: LVEF measured during hospitalization for MI was a determinant for HRQoL 2.5 years later.en
dc.language.isoenen
dc.publisherBioMed Centralen
dc.relation.urlhttp://www.biomedcentral.com/1471-2261/8/28en
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Kardiologi: 771en
dc.subject.meshAgeden
dc.subject.meshCohort Studiesen
dc.subject.meshFemaleen
dc.subject.meshHospitalizationen
dc.subject.meshHumansen
dc.subject.meshLogistic Modelsen
dc.subject.meshMaleen
dc.subject.meshMyocardial Infarctionen
dc.subject.meshNorwayen
dc.subject.meshQuality of Lifeen
dc.subject.meshQuestionnairesen
dc.subject.meshStroke Volumeen
dc.subject.meshTime Factorsen
dc.subject.meshTreatment Outcomeen
dc.subject.meshVentricular Function, Leften
dc.titleHealth-related quality of life after myocardial infarction is associated with level of left ventricular ejection fraction.en
dc.typeJournal articleen
dc.typepeer revieweden
dc.contributor.departmentNorwegian Knowledge Centre for the Health Services, Oslo, Norway. kjell.pettersen@medisin.uio.noen
dc.identifier.journalBMC cardiovascular disordersen
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