Pulmonary tuberculosis among people living with HIV/AIDS attending care and treatment in rural northern Tanzania.

2.50
Hdl Handle:
http://hdl.handle.net/10143/41682
Title:
Pulmonary tuberculosis among people living with HIV/AIDS attending care and treatment in rural northern Tanzania.
Authors:
Ngowi, Bernard J; Mfinanga, Sayoki G; Bruun, Johan N; Morkve, Odd
Citation:
BMC public health 2008, 8:341
Additional Links:
http://www.biomedcentral.com/1471-2458/8/341

Full metadata record

DC FieldValue Language
dc.contributor.authorNgowi, Bernard J-
dc.contributor.authorMfinanga, Sayoki G-
dc.contributor.authorBruun, Johan N-
dc.contributor.authorMorkve, Odd-
dc.date.accessioned2008-12-02T11:29:35Z-
dc.date.available2008-12-02T11:29:35Z-
dc.date.issued2008-
dc.identifier.citationBMC public health 2008, 8:341en
dc.identifier.issn1471-2458-
dc.identifier.pmid18826574-
dc.identifier.doi10.1186/1471-2458-8-341-
dc.identifier.urihttp://hdl.handle.net/10143/41682-
dc.description.abstractBACKGROUND: Tuberculosis is the commonest opportunistic infection and the number one cause of death in HIV/AIDS patients in developing countries. To address the extent of the tuberculosis HIV coinfection in rural Tanzania we conducted a cross sectional study including HIV/AIDS patients attending care and treatment clinic from September 2006 to March 2007. METHODS: Sputum samples were collected for microscopy, culture and drug susceptibility testing. Chest X-ray was done for those patients who consented. Blood samples were collected for CD4+ T cells count. RESULTS: The prevalence of tuberculosis was 20/233 (8.5%). Twenty (8.5%) sputum samples were culture positive. Eight of the culture positive samples (40%) were smear positive. Fifteen (75%) of these patients neither had clinical symptoms nor chest X-ray findings suggestive of tuberculosis. Nineteen isolates (95%) were susceptible to rifampicin, isoniazid, streptomycin and ethambutol (the first line tuberculosis drugs). One isolate (5%) from HIV/tuberculosis coinfected patients was resistant to isoniazid. No cases of multi- drug resistant tuberculosis were identified. CONCLUSION: We found high prevalence of tuberculosis disease in this setting. Chest radiograph suggestive of tuberculosis and clinical symptoms of fever and cough were uncommon findings in HIV/tuberculosis coinfected patients. Tuberculosis can occur at any stage of CD4+T cells depletion.en
dc.language.isoenen
dc.relation.urlhttp://www.biomedcentral.com/1471-2458/8/341en
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Lungesykdommer: 777en
dc.subject.meshAIDS-Related Opportunistic Infectionsen
dc.subject.meshAdolescenten
dc.subject.meshAdulten
dc.subject.meshAnti-Retroviral Agentsen
dc.subject.meshAntitubercular Agentsen
dc.subject.meshCD4 Lymphocyte Counten
dc.subject.meshCross-Sectional Studiesen
dc.subject.meshFemaleen
dc.subject.meshHIV Infectionsen
dc.subject.meshHumansen
dc.subject.meshMaleen
dc.subject.meshMicrobial Sensitivity Testsen
dc.subject.meshMiddle Ageden
dc.subject.meshPrevalenceen
dc.subject.meshQuestionnairesen
dc.subject.meshRural Populationen
dc.subject.meshSputumen
dc.subject.meshTanzaniaen
dc.subject.meshTuberculosis, Pulmonaryen
dc.titlePulmonary tuberculosis among people living with HIV/AIDS attending care and treatment in rural northern Tanzania.en
dc.typepeer revieweden
dc.contributor.departmentHaydom Lutheran Hospital, Mbulu District, Manyara Region, Tanzania. bernard.ngowi@student.uib.noen
dc.contributor.departmentUllevaal University Hospitalen
dc.identifier.journalBMC public healthen
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