Levels of ethyl glucuronide and ethyl sulfate in oral fluid, blood, and urine after use of mouthwash and ingestion of nonalcoholic wine.

2.50
Hdl Handle:
http://hdl.handle.net/10143/116378
Title:
Levels of ethyl glucuronide and ethyl sulfate in oral fluid, blood, and urine after use of mouthwash and ingestion of nonalcoholic wine.
Authors:
Høiseth, Gudrun; Yttredal, Borghild; Karinen, Ritva; Gjerde, Hallvard; Christophersen, Asbjørg
Citation:
Journal of analytical toxicology 2010, 34 (2):84-8
Additional Links:
http://www.jatox.com/index.php/Articles/Levels-of-Ethyl-Glucuronide-and-Ethyl-Sulfate-in-Oral-Fluid-Blood-and-Urine-After-Use-of-Mouthwash-and-Ingestion-of-Nonalcoholic-Wine.html

Full metadata record

DC FieldValue Language
dc.contributor.authorHøiseth, Gudrunen
dc.contributor.authorYttredal, Borghilden
dc.contributor.authorKarinen, Ritvaen
dc.contributor.authorGjerde, Hallvarden
dc.contributor.authorChristophersen, Asbjørgen
dc.date.accessioned2010-11-26T11:29:37Z-
dc.date.available2010-11-26T11:29:37Z-
dc.date.issued2010-
dc.identifier.citationJournal of analytical toxicology 2010, 34 (2):84-8en
dc.identifier.issn1945-2403-
dc.identifier.pmid20223100-
dc.identifier.urihttp://hdl.handle.net/10143/116378-
dc.description.abstractThe aim of this study is to investigate the concentrations of ethyl glucuronide (EtG) in oral fluid and both EtG and ethyl sulfate (EtS) in blood and urine following intense use of mouthwash and ingestion of nonalcoholic wine, which are proven to contain 3 mg/L EtG, 1.5 mg/L EtS, and 0.2 g/L ethanol. Twelve subjects participated in a controlled experiment. All subjects ingesting nonalcoholic wine showed urine samples negative for EtG but positive for EtS (Cmax 2.15 mg/L). All four subjects using mouthwash were negative for EtG and EtS in urine. All samples of oral fluid were negative for EtG and all samples of blood were negative for EtG and EtS. This study showed that ingestion of EtG and EtS as components of nonalcoholic wine lead to detection of urine EtS only, suggesting superior bioavailability of orally ingested EtS compared to EtG. This possibility of false-positive EtS results in urine after ingestion of nonalcoholic wine is important to remember when using EtG and EtS as relapse markers for alcohol. Finally, the study showed that a positive EtG or EtS result after accidental alcohol exposure is unlikely in blood and oral fluid.en
dc.language.isoenen
dc.relation.urlhttp://www.jatox.com/index.php/Articles/Levels-of-Ethyl-Glucuronide-and-Ethyl-Sulfate-in-Oral-Fluid-Blood-and-Urine-After-Use-of-Mouthwash-and-Ingestion-of-Nonalcoholic-Wine.htmlen
dc.subject.meshAdulten
dc.subject.meshAlcohol Drinkingen
dc.subject.meshAlcoholic Beveragesen
dc.subject.meshBiological Markersen
dc.subject.meshCreatinineen
dc.subject.meshFalse Positive Reactionsen
dc.subject.meshFemaleen
dc.subject.meshGlucuronatesen
dc.subject.meshHumansen
dc.subject.meshMaleen
dc.subject.meshMouthwashesen
dc.subject.meshSalivaen
dc.subject.meshSulfuric Acid Estersen
dc.subject.meshWineen
dc.subject.meshYoung Adulten
dc.titleLevels of ethyl glucuronide and ethyl sulfate in oral fluid, blood, and urine after use of mouthwash and ingestion of nonalcoholic wine.en
dc.typeJournal articleen
dc.typepeer reviewed-
dc.contributor.departmentNorwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Oslo, Norway. Gudrun.Hoiseth@fhi.noen
dc.identifier.journalJournal of analytical toxicologyen

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